Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858769 | 0.96 | S1PR1 (0.78) | S1PR1S1PR3 | |
| SCHEMBL1854979 | 0.94 | S1PR1 (0.79) | S1PR1S1PR3 | |
| SCHEMBL1858256 | 0.90 | S1PR1 (0.78) | S1PR1S1PR3 | |
| SCHEMBL1858713 | 0.89 | S1PR1 (0.82) | S1PR1S1PR3 | |
| SCHEMBL1862165 | 0.88 | S1PR1 (0.92) | S1PR1S1PR3 | |
| SCHEMBL1858716 | 0.88 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL1859848 | 0.88 | S1PR1 (0.65) | S1PR1S1PR3 | |
| SCHEMBL1853090 | 0.88 | S1PR1 (0.79) | S1PR1S1PR3 | |
| SCHEMBL1858203 | 0.87 | S1PR1 (0.80) | S1PR1S1PR3 | |
| SCHEMBL1860222 | 0.87 | S1PR1 (0.86) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039644-B2 | Hydrogenated benzo (C) thiophene derivatives as immunomodulators | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-10-18 | — | — | US | claimed |
| EP-1863787-B1 | HYDOGRENATED BENZO[C]THIOPHENE DERIVATIVES AS IMMUNOMODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-05-25 | — | — | EP | claimed |
| US-8039644-B2 | Hydrogenated benzo (C) thiophene derivatives as immunomodulators | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-10-18 | — | — | US | disclosed |
| EP-1863787-B1 | HYDOGRENATED BENZO[C]THIOPHENE DERIVATIVES AS IMMUNOMODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-05-25 | — | — | EP | disclosed |