Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 20/20 | 0.82 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL325839 | 0.90 | S1PR5 (1.00) | S1PR5S1PR3S1PR1 | |
| Hydrochloric Acid SCHEMBL15137337 | 0.89 | S1PR5 (0.98) | S1PR5S1PR3S1PR1 | |
| SCHEMBL23325971 | 0.83 | S1PR5 (0.71) | S1PR5S1PR3S1PR1 | |
| SCHEMBL18537284 | 0.83 | S1PR5 (0.73) | S1PR5S1PR3S1PR1 | |
| SCHEMBL326160 | 0.80 | S1PR5 (0.80) | S1PR5S1PR3S1PR1 | |
| SCHEMBL15137011 | 0.79 | S1PR5 (0.82) | S1PR5S1PR3S1PR1 | |
| SCHEMBL326386 | 0.78 | S1PR5 (0.70) | S1PR5S1PR3S1PR1 | |
| SCHEMBL326387 | 0.78 | S1PR5 (0.70) | S1PR5S1PR3S1PR1 | |
| Hydrochloric Acid SCHEMBL326397 | 0.78 | S1PR5 (0.81) | S1PR5S1PR3S1PR1 | |
| Hydrochloric Acid SCHEMBL15136798 | 0.78 | S1PR5 (0.70) | S1PR5S1PR3S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3144312-A1 | SPIRO-CYCLIC AMINE DERIVATIVES AS S1P MODULATORS | AbbVie B.V. (NL) | 2017-03-22 | — | — | EP | disclosed |
| EP-2590955-B9 | SPIRO-CYCLIC AMINE DERIVATIVES AS S1P MODULATORS | ABBVIE BV (NL) | 2017-02-22 | — | — | EP | disclosed |