Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.88 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.88 |
| ▸ | FOXM1 | Q08050 | 3/20 | 0.88 |
| ▸ | TP53 | P04637 | 2/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.74 |
| ▸ | MEN1 | O00255 | 8/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | HPGD | P15428 | 5/20 | 0.74 |
| ▸ | POLB | P06746 | 5/20 | 0.74 |
| ▸ | CRHBP | P24387 | 2/20 | 0.74 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19853111 | 0.94 | MAPT (1.00) | MAPTRXFP1FOXM1TP53KMT2A | |
| SCHEMBL19000365 | 0.94 | MAPT (0.86) | MAPTRXFP1FOXM1TP53KMT2A | |
| SCHEMBL29558180 | 0.94 | MAPT (1.00) | MAPTRXFP1FOXM1TP53KMT2A | |
| SCHEMBL13186381 | 0.94 | MAPT (0.86) | MAPTRXFP1FOXM1TP53KMT2A | |
| SCHEMBL14969380 | 0.93 | MAPT (0.85) | MAPTRXFP1FOXM1TP53KMT2A | |
| SCHEMBL432256 | 0.89 | MAPT (0.79) | MAPTRXFP1FOXM1TP53KMT2A | |
| SCHEMBL15788394 | 0.89 | MAPT (0.79) | MAPTRXFP1FOXM1TP53KMT2A | |
| SCHEMBL13568307 | 0.84 | KMT2A (0.76) | MAPTRXFP1FOXM1TP53KMT2A | |
| SCHEMBL14954964 | 0.84 | LIMK1 (0.84) | MAPTRXFP1FOXM1TP53KMT2A | |
| SCHEMBL4193459 | 0.84 | LIMK1 (1.00) | MAPTRXFP1FOXM1TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2400845-B1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | SIGA TECH INC (US) | 2017-02-22 | — | — | EP | disclosed |