Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN4 | P29074 | 1/20 | 0.50 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18538254 | 1.00 | PTPN2 (0.50) | PTPN2PTPN1PTPN4PTPN9PTPN11 | |
| SCHEMBL18538308 | 0.87 | ING2 (0.55) | PTPN2PTPN1PTPN4PTPN9PTPN11 | |
| SCHEMBL18538305 | 0.87 | ING2 (0.55) | PTPN2PTPN1PTPN4PTPN9PTPN11 | |
| SCHEMBL18538258 | 0.86 | PTPN1 (0.46) | PTPN2PTPN1PTPN4PTPN9PTPN11 | |
| SCHEMBL18538257 | 0.86 | PTPN1 (0.46) | PTPN2PTPN1PTPN4PTPN9PTPN11 | |
| SCHEMBL18538256 | 0.86 | PTPN1 (0.46) | PTPN2PTPN1PTPN4PTPN9PTPN11 | |
| SCHEMBL18538267 | 0.84 | CD69 (0.50) | PTPN2PTPN1PTPN4PTPN9PTPN11 | |
| SCHEMBL18538270 | 0.82 | PTPN2 (0.40) | PTPN2PTPN1PTPN4PTPN9PTPN11 | |
| SCHEMBL18538251 | 0.82 | PTPN2 (0.40) | PTPN2PTPN1PTPN4PTPN9PTPN11 | |
| SCHEMBL18538262 | 0.82 | PTPN2 (0.40) | PTPN2PTPN1PTPN4PTPN9PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170052154-A1 | COMPOUNDS AND CONJUGATES FOR IDENTIFYING AND SEPARATING POST-TRANSLATIONALLY MODIFIED ANALYTES | UVIC INDUSTRY PARTNERSHIPS INC. (CA) | 2017-02-23 | — | — | US | disclosed |