Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GCK | P35557 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62507 | 0.90 | ABCB1 (0.45) | ABCB1NPC1RAB9ATP53NR3C2 | |
| SCHEMBL65051 | 0.90 | HDAC1 (0.44) | ABCB1NPC1RAB9ATP53NR3C2 | |
| SCHEMBL65150 | 0.90 | ABCB1 (0.49) | ABCB1NPC1RAB9ANR3C2SMN1; SMN2 | |
| SCHEMBL64528 | 0.88 | P4HTM (0.53) | ABCB1NR3C2ROCK2ROCK1MEN1 | |
| SCHEMBL64118 | 0.88 | KCNQ3 (0.52) | ABCB1NPC1RAB9ANR3C2SMN1; SMN2 | |
| SCHEMBL62361 | 0.88 | ABCB1 (0.47) | ABCB1RAB9ANR3C2SMN1; SMN2ROCK2 | |
| SCHEMBL62554 | 0.88 | ABCB1 (0.47) | ABCB1RAB9ANR3C2SMN1; SMN2ROCK2 | |
| SCHEMBL63946 | 0.87 | NPC1 (0.41) | ABCB1NPC1RAB9ATP53NR3C2 | |
| SCHEMBL1856714 | 0.86 | ABCB1 (0.44) | ABCB1RAB9ANR3C2SMN1; SMN2ROCK2 | |
| SCHEMBL64697 | 0.86 | ABCB1 (0.46) | ABCB1NPC1RAB9ATP53NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125748-B1 | ACYLAMINOPYRAZOLES AS FGFR INHIBITORS | ASTRAZENECA AB (SE) | 2011-05-25 | — | — | EP | claimed |