Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD5 | P21918 | 1/20 | 0.68 |
| ▸ | SCNN1A | P37088 | 1/20 | 0.68 |
| ▸ | SCNN1B | P51168 | 1/20 | 0.68 |
| ▸ | SCNN1G | P51170 | 1/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.35 |
| ▸ | ATR | Q13535 | 4/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18541253 | 0.96 | DRD5 (0.70) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541357 | 0.93 | DRD5 (0.74) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541249 | 0.92 | DRD5 (0.73) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541360 | 0.91 | DRD5 (0.81) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538896 | 0.91 | DRD5 (0.83) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541231 | 0.89 | DRD5 (0.56) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541230 | 0.88 | DRD5 (0.58) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538913 | 0.86 | DRD5 (0.85) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541248 | 0.86 | DRD5 (0.64) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541356 | 0.86 | DRD5 (0.64) | DRD5SCNN1ASCNN1BSCNN1GHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017028926-A1 | NOVEL ANNELATED BENZAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-02-23 | — | — | WO | disclosed |