Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD5 | P21918 | 1/20 | 0.53 |
| ▸ | SCNN1A | P37088 | 1/20 | 0.53 |
| ▸ | SCNN1B | P51168 | 1/20 | 0.53 |
| ▸ | SCNN1G | P51170 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | ATR | Q13535 | 11/20 | 0.33 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.33 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 4/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18541250 | 0.93 | DRD5 (0.55) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538930 | 0.91 | DRD5 (0.64) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541251 | 0.89 | DRD5 (0.58) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541232 | 0.88 | DRD5 (0.56) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538916 | 0.85 | DRD5 (0.62) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538928 | 0.85 | DRD5 (0.66) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538922 | 0.81 | DRD5 (0.69) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18551181 | 0.81 | DRD5 (0.45) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541299 | 0.81 | DRD5 (0.48) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541246 | 0.80 | DRD5 (0.57) | DRD5SCNN1ASCNN1BSCNN1GHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017028926-A1 | NOVEL ANNELATED BENZAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-02-23 | — | — | WO | disclosed |