Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.68 |
| ▸ | ACHE | P22303 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.65 |
| ▸ | CDC25A | P30304 | 3/20 | 0.65 |
| ▸ | POLA1 | P09884 | 1/20 | 0.65 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 3/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | VDR | P11473 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MDM4 | O15151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553921 | 1.00 | BCHE (0.68) | BCHEACHECYP2C19CYP2D6INPP5D | |
| SCHEMBL9580404 | 1.00 | BCHE (0.68) | BCHEACHECYP2C19CYP2D6INPP5D | |
| SCHEMBL12279967 | 1.00 | BCHE (0.68) | BCHEACHECYP2C19CYP2D6INPP5D | |
| SCHEMBL18541463 | 1.00 | BCHE (0.68) | BCHEACHECYP2C19CYP2D6INPP5D | |
| SCHEMBL21206235 | 1.00 | BCHE (0.68) | BCHEACHECYP2C19CYP2D6INPP5D | |
| SCHEMBL20370390 | 0.91 | CYP2C19 (0.62) | BCHEACHECYP2C19CYP2D6INPP5D | |
| SCHEMBL20374713 | 0.91 | CYP2C19 (0.62) | BCHEACHECYP2C19CYP2D6INPP5D | |
| SCHEMBL17817066 | 0.89 | CYP2C19 (0.66) | BCHEACHECYP2C19CYP2D6INPP5D | |
| SCHEMBL23635434 | 0.89 | CYP2D6 (0.62) | BCHEACHECYP2C19CYP2D6INPP5D | |
| Hydrochloric Acid SCHEMBL8003235 | 0.89 | INPP5D (0.66) | BCHEACHECYP2C19CYP2D6INPP5D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11319336-B2 | Ship inhibitors and uses thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2022-05-03 | — | — | US | disclosed |
| US-20170051006-A1 | SHIP INHIBITORS AND USES THEREOF | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11319336-B2 | Ship inhibitors and uses thereof | PPP5C, DUSP1, DUSP5 | BCHE 4267/4885ACHE 3989/4885CYP2C19 4686/4885 |
| US-20170051006-A1 | SHIP INHIBITORS AND USES THEREOF | PPP5C, DUSP1, DUSP5 | BCHE 4267/4885ACHE 3989/4885CYP2C19 4686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.