Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 14/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20143474 | 0.88 | P2RX4 (0.59) | P2RX4MAPTMEN1KMT2A | |
| SCHEMBL14972509 | 0.85 | P2RX4 (0.55) | P2RX4MAPTMEN1KMT2ARAB9A | |
| SCHEMBL14972561 | 0.85 | P2RX4 (0.55) | P2RX4MAPTMEN1KMT2ARAB9A | |
| SCHEMBL14972590 | 0.82 | P2RX4 (0.59) | P2RX4MAPTMEN1KMT2ARAB9A | |
| SCHEMBL14972537 | 0.82 | P2RX4 (0.54) | P2RX4MAPTMEN1KMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL14972534 | 0.81 | P2RX4 (0.54) | P2RX4MAPTMEN1KMT2AALOX15 | |
| SCHEMBL14972529 | 0.79 | P2RX4 (0.50) | P2RX4MAPTMEN1KMT2AALOX15 | |
| SCHEMBL14972867 | 0.79 | P2RX4 (0.50) | P2RX4MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL14972501 | 0.79 | P2RX4 (0.48) | P2RX4MAPTMEN1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL14972545 | 0.78 | P2RX4 (0.49) | P2RX4MAPTMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2803662-B1 | P2X4 RECEPTOR ANTAGONIST | NIPPON CHEMIPHAR CO (JP) | 2017-03-01 | — | — | EP | claimed |