Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538145 | 0.86 | ABCB1 (0.69) | ABCB1ABCG2POLBALDH1A1HPGD | |
| SCHEMBL4538147 | 0.86 | ABCB1 (0.69) | ABCB1ABCG2POLBALDH1A1HPGD | |
| SCHEMBL18543730 | 0.86 | ABCB1 (0.59) | ABCB1ABCG2KMT2APOLBALDH1A1 | |
| SCHEMBL15640200 | 0.85 | ABCB1 (0.68) | ABCB1ABCG2POLBALDH1A1HPGD | |
| SCHEMBL1958136 | 0.85 | ABCB1 (0.57) | ABCB1ABCG2KMT2AMEN1POLB | |
| SCHEMBL18543735 | 0.85 | ABCB1 (0.57) | ABCB1ABCG2KMT2AMEN1POLB | |
| SCHEMBL1958134 | 0.85 | ABCB1 (0.57) | ABCB1ABCG2KMT2AMEN1POLB | |
| SCHEMBL18543729 | 0.82 | ABCB1 (0.59) | ABCB1ABCG2KMT2APOLBALDH1A1 | |
| SCHEMBL18543728 | 0.81 | ABCB1 (0.68) | ABCB1ABCG2KMT2AMEN1POLB | |
| SCHEMBL18543726 | 0.81 | ABCB1 (0.68) | ABCB1ABCG2KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332905-B1 | BCRP/ABCG2 Inhibitor | YAKULT HONSHA KK (JP) | 2017-03-01 | — | — | EP | claimed |