Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723539 | 0.81 | PDE10A (0.39) | EGFRMAP4K4KCNH2MEN1KMT2A | |
| SCHEMBL23084868 | 0.81 | KCNH2 (0.44) | EGFRMAP4K4KCNH2MEN1KMT2A | |
| SCHEMBL29692873 | 0.80 | EGFR (0.38) | EGFRMAP4K4KCNH2MEN1KMT2A | |
| SCHEMBL592797 | 0.80 | EGFR (0.44) | EGFRMAP4K4KCNH2MEN1KMT2A | |
| SCHEMBL29514474 | 0.80 | EGFR (0.44) | EGFRMAP4K4KCNH2MEN1KMT2A | |
| SCHEMBL590199 | 0.80 | MAP4K4 (0.44) | EGFRMAP4K4KCNH2MEN1KMT2A | |
| SCHEMBL592329 | 0.80 | EGFR (0.38) | EGFRMAP4K4KCNH2MEN1KMT2A | |
| SCHEMBL29692936 | 0.80 | PDE2A (0.39) | EGFRMAP4K4KCNH2MEN1KMT2A | |
| SCHEMBL590921 | 0.80 | PDE2A (0.39) | EGFRMAP4K4KCNH2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3578561 | 0.79 | MAP4K4 (0.43) | EGFRMAP4K4KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022058920-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-24 | — | — | WO | disclosed |
| WO-2017029602-A2 | COMPOUNDS FOR USE IN ANTIBACTERIAL APPLICATIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-02-23 | — | — | WO | disclosed |