Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 9/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.45 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.45 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12008465 | 0.86 | POLB (0.71) | MEN1KMT2APOLBUSP2NSD2 | |
| SCHEMBL12008495 | 0.84 | MEN1 (0.74) | MEN1KMT2APOLBUSP2NSD2 | |
| SCHEMBL12008581 | 0.75 | KMT2A (0.80) | MEN1KMT2APOLBGFERMAPT | |
| SCHEMBL12008631 | 0.75 | FFAR1 (0.69) | MEN1KMT2APOLBMAPTCACNA1B | |
| SCHEMBL12008724 | 0.74 | POLB (0.77) | MEN1KMT2APOLBUSP2NSD2 | |
| SCHEMBL12008434 | 0.72 | CISD1 (0.72) | MEN1KMT2APOLBMAPTCACNA1B | |
| SCHEMBL12008714 | 0.72 | KMT2A (0.76) | MEN1KMT2APOLBUSP2NSD2 | |
| SCHEMBL12008719 | 0.72 | KMT2A (0.70) | MEN1KMT2APOLBUSP2NSD2 | |
| SCHEMBL12008584 | 0.72 | MEN1 (0.87) | MEN1KMT2APOLBUSP2NSD2 | |
| SCHEMBL12008586 | 0.72 | MEN1 (1.00) | MEN1KMT2APOLBUSP2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170049751-A1 | OXAZOLE AND THIAZOLE COMPOUNDS AS BETA-CATENIN MODULATORS AND USES THEREOF | DASGUPTA RAMANUJ (US) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170049751-A1 | OXAZOLE AND THIAZOLE COMPOUNDS AS BETA-CATENIN MODULATORS AND USES THEREOF | CTNNB1, CTNNA1, CTNNBL1 | MEN1 4655/4885KMT2A 4591/4885POLB 2088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.