SCHEMBL18545545

SCHEMBL18545545

CCNCC1CC(C)(C)N(O)C1(C)C

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8260963 0.81 GAA (0.47) GAAL3MBTL1
SCHEMBL13333336 0.81 GAA (0.40) GAAL3MBTL1
SCHEMBL13979303 0.79 GAA (0.39) GAAL3MBTL1
SCHEMBL12846238 0.78 GAA (0.52) GAAL3MBTL1
SCHEMBL20464752 0.76 GAA (0.42) GAAL3MBTL1
SCHEMBL12200994 0.76 GAA (0.42) GAAL3MBTL1
SCHEMBL12846336 0.76 GAA (0.39) GAAL3MBTL1
SCHEMBL17931191 0.76 GAA (0.54) GAAL3MBTL1
SCHEMBL17978418 0.75 GAA (0.41) GAAL3MBTL1
SCHEMBL4853121 0.74 GAA (0.52) GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017031239-A1 NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-02-23 WO disclosed