Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377190 | 1.00 | GAA (0.56) | GAAL3MBTL1ALDH1A1ALOX15KDM4E | |
| SCHEMBL10597667 | 0.76 | GAA (0.41) | GAAL3MBTL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13060033 | 0.76 | GAA (0.52) | GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7607254 | 0.75 | GAA (0.40) | GAAL3MBTL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL143973 | 0.74 | GAA (0.48) | GAAL3MBTL1ALDH1A1ALOX15KDM4E | |
| SCHEMBL16564662 | 0.73 | GAA (0.39) | GAAL3MBTL1 | |
| SCHEMBL14165287 | 0.72 | GAA (0.31) | GAAL3MBTL1 | |
| SCHEMBL18545631 | 0.72 | GAA (0.58) | GAAL3MBTL1ALDH1A1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL5044550 | 0.72 | GAA (0.46) | GAAL3MBTL1ALDH1A1ALOX15KDM4E | |
| SCHEMBL7636857 | 0.72 | GAA (0.58) | GAAL3MBTL1ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017031239-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-23 | — | — | WO | disclosed |