Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2551109 | 0.98 | TSHR (0.44) | TSHRZDHHC20ZDHHC2TAS1R3TAS1R1 | |
| SCHEMBL28662765 | 0.87 | TSHR (0.35) | TSHRZDHHC20ZDHHC2ACACBALDH1A1 | |
| SCHEMBL309296 | 0.85 | TSHR (0.48) | TSHRZDHHC20ZDHHC2ACACBALDH1A1 | |
| SCHEMBL7588962 | 0.84 | TSHR (0.41) | TSHRZDHHC20ZDHHC2TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL27897135 | 0.84 | TSHR (0.44) | TSHRZDHHC20ZDHHC2ACACBALDH1A1 | |
| Fluoride Ion SCHEMBL17105891 | 0.83 | TSHR (0.47) | TSHRZDHHC20ZDHHC2ACACBALDH1A1 | |
| Bromide SCHEMBL17105893 | 0.83 | TSHR (0.47) | TSHRZDHHC20ZDHHC2ACACBALDH1A1 | |
| Iodide SCHEMBL3132818 | 0.83 | TSHR (0.47) | TSHRZDHHC20ZDHHC2ACACBALDH1A1 | |
| Hydrochloric Acid SCHEMBL127416 | 0.83 | TSHR (0.47) | TSHRZDHHC20ZDHHC2ACACBALDH1A1 | |
| Water SCHEMBL2355005 | 0.83 | TSHR (0.47) | TSHRZDHHC20ZDHHC2ACACBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170056834-A1 | MULTILAYER COATINGS AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2017-03-02 | — | — | US | disclosed |