Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 16/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.67 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.67 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.67 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18549146 | 1.00 | HDAC1 (0.67) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL18549258 | 0.91 | HDAC1 (0.80) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL18549259 | 0.91 | HDAC1 (0.80) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL18549216 | 0.89 | HDAC1 (0.67) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL18549219 | 0.89 | HDAC1 (0.67) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL18549183 | 0.89 | HDAC3 (0.52) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL17173783 | 0.89 | HDAC3 (0.52) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL18549261 | 0.89 | HDAC1 (0.69) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL17173412 | 0.89 | HDAC1 (0.69) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL18549176 | 0.89 | HDAC1 (0.67) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246455-B2 | Histone deacetylase inhibitors | TAIPEI MEDICAL UNIVERSITY (TW) | 2019-04-02 | — | — | US | disclosed |
| US-20170057956-A1 | HISTONE DEACETYLASE INHIBITORS | TAIPEI MEDICAL UNIVERSITY (TW) | 2017-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246455-B2 | Histone deacetylase inhibitors | HDAC1, HDAC2, HDAC5 | HDAC1 1/4885HDAC3 4/4885HDAC4 9/4885 |
| US-20170057956-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC2, HDAC5 | HDAC1 1/4885HDAC3 4/4885HDAC4 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.