Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 18/20 | 0.82 |
| ▸ | HTR2A | P28223 | 3/20 | 0.82 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.82 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.82 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.82 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.82 |
| ▸ | HTR3A | P46098 | 1/20 | 0.82 |
| ▸ | HTR6 | P50406 | 1/20 | 0.82 |
| ▸ | HTR2B | P41595 | 13/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1620274 | 0.90 | HTR2C (1.00) | HTR2CHTR2ACHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL1622319 | 0.89 | HTR2C (0.97) | HTR2CHTR2ACHRM4CHRM5CHRM1 | |
| SCHEMBL18550078 | 0.80 | HTR2C (0.62) | HTR2CHTR2ACHRM4CHRM5CHRM1 | |
| SCHEMBL1624015 | 0.78 | HTR2C (1.00) | HTR2CHTR2ACHRM4CHRM5CHRM1 | |
| SCHEMBL1621843 | 0.78 | HTR2C (1.00) | HTR2CHTR2ACHRM4CHRM5CHRM1 | |
| SCHEMBL1623428 | 0.76 | HTR2C (1.00) | HTR2CHTR2ACHRM4CHRM5CHRM1 | |
| SCHEMBL1620487 | 0.76 | HTR2C (1.00) | HTR2CHTR2ACHRM4CHRM5CHRM1 | |
| SCHEMBL1623007 | 0.76 | HTR2C (1.00) | HTR2CHTR2ACHRM4CHRM5CHRM1 | |
| SCHEMBL1622904 | 0.75 | HTR2C (1.00) | HTR2CHTR2ACHRM4CHRM5CHRM1 | |
| SCHEMBL1622167 | 0.75 | HTR2C (1.00) | HTR2CHTR2ACHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368107-B | Fused heterocyclic compounds as S1P modulators | 艾伯维公司 | 2021-11-26 | — | — | CN | disclosed |
| US-10556907-B2 | Fused heterocyclic compounds as S1P modulators | AbbVie Deutschland GmbH & Co. KG (DE) | 2020-02-11 | — | — | US | disclosed |
| US-10556907-B2 | Fused heterocyclic compounds as S1P modulators | AbbVie Deutschland GmbH & Co. KG (DE) | 2020-02-11 | — | — | US | disclosed |
| EP-3341369-A1 | FUSED HETEROCYCLIC COMPOUNDS AS S1P MODULATORS | AbbVie Inc. (US) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017036978-A1 | FUSED HETEROCYCLIC COMPOUNDS AS S1P MODULATORS | ABBVIE INC. (US) | 2017-03-09 | — | — | WO | disclosed |
| US-20170057966-A1 | FUSED HETEROCYCLIC COMPOUNDS AS S1P MODULATORS | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-03-02 | — | — | US | disclosed |
| US-20170057966-A1 | FUSED HETEROCYCLIC COMPOUNDS AS S1P MODULATORS | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-03-02 | — | — | US | disclosed |
| US-20170057966-A1 | FUSED HETEROCYCLIC COMPOUNDS AS S1P MODULATORS | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170057966-A1 | FUSED HETEROCYCLIC COMPOUNDS AS S1P MODULATORS | S1PR1, S1PR2, S1PR3 | HTR2C 835/4885HTR2A 455/4885CHRM4 1900/4885 |
| US-10556907-B2 | Fused heterocyclic compounds as S1P modulators | S1PR1, S1PR2, S1PR3 | HTR2C 835/4885HTR2A 455/4885CHRM4 1900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.