Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18550557 | 1.00 | HRH4 (0.60) | HRH4HRH3 | |
| SCHEMBL604411 | 0.83 | HRH4 (0.63) | HRH4HRH3 | |
| SCHEMBL604412 | 0.83 | HRH4 (0.63) | HRH4HRH3 | |
| SCHEMBL606479 | 0.79 | HRH4 (0.97) | HRH4HRH3 | |
| SCHEMBL603649 | 0.79 | HRH4 (0.97) | HRH4HRH3 | |
| SCHEMBL604664 | 0.79 | HRH4 (0.70) | HRH4HRH3 | |
| SCHEMBL605630 | 0.78 | HRH4 (1.00) | HRH4HRH3 | |
| SCHEMBL605186 | 0.78 | HRH4 (1.00) | HRH4HRH3 | |
| SCHEMBL603079 | 0.73 | HRH4 (0.89) | HRH4HRH3 | |
| SCHEMBL605586 | 0.73 | HRH4 (0.97) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10195195-B2 | Selective histamine H4 receptor antagonists for the treatment of vestibular disorders | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2019-02-05 | — | — | US | disclosed |
| US-20170056397-A1 | SELECTIVE HISTAMINE H4 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF VESTIBULAR DISORDERS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2017-03-02 | — | — | US | disclosed |