Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | SCNN1A | P37088 | 1/20 | 0.49 |
| ▸ | SCNN1B | P51168 | 1/20 | 0.49 |
| ▸ | SCNN1G | P51170 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18551673 | 0.96 | DRD5 (0.50) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18550969 | 0.92 | DRD5 (0.49) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18551278 | 0.91 | DRD5 (0.57) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18550532 | 0.91 | DRD5 (0.60) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541246 | 0.88 | DRD5 (0.57) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18551674 | 0.86 | DRD5 (0.61) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18539745 | 0.85 | DRD5 (0.61) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18550876 | 0.83 | DRD5 (0.61) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18551181 | 0.83 | DRD5 (0.45) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18551435 | 0.82 | DRD5 (0.49) | DRD5SCNN1ASCNN1BSCNN1GHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017028927-A1 | NOVEL ANNELATED PHENOXYACETAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-02-23 | — | — | WO | disclosed |