SCHEMBL18552

SCHEMBL18552

COC(=O)C1CCCCC1

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.68
POLB P06746 1/20 0.56
ALDH1A1 P00352 3/20 0.51
TP53 P04637 1/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
CHRNB2 P17787 2/20 0.45
CHRNA4 P43681 2/20 0.45
CHRNB4 P30926 1/20 0.45
CHRNA3 P32297 1/20 0.45
CHRNA7 P36544 1/20 0.45
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18557032 1.00 SMN1; SMN2 (0.68) SMN1; SMN2POLBALDH1A1TP53CES2
SCHEMBL30542346 1.00 SMN1; SMN2 (0.68) SMN1; SMN2POLBALDH1A1TP53CES2
SCHEMBL7119913 1.00 SMN1; SMN2 (0.68) SMN1; SMN2POLBALDH1A1TP53CES2
SCHEMBL30542347 1.00 SMN1; SMN2 (0.68) SMN1; SMN2POLBALDH1A1TP53CES2
SCHEMBL15443235 1.00 SMN1; SMN2 (0.68) SMN1; SMN2POLBALDH1A1TP53CES2
SCHEMBL18760457 1.00 SMN1; SMN2 (0.68) SMN1; SMN2POLBALDH1A1TP53CES2
SCHEMBL12326212 1.00 SMN1; SMN2 (0.68) SMN1; SMN2POLBALDH1A1TP53CES2
SCHEMBL1818944 1.00 SMN1; SMN2 (0.68) SMN1; SMN2POLBALDH1A1TP53CES2
SCHEMBL29058069 1.00 SMN1; SMN2 (0.68) SMN1; SMN2POLBALDH1A1TP53CES2
SCHEMBL6966832 1.00 SMN1; SMN2 (0.68) SMN1; SMN2POLBALDH1A1TP53CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3835 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12416637-B2 Biomarkers for irritable bowel syndrome UNIV LIVERPOOL (GB) 2025-09-16 US claimed
CN-119161372-A Bimetallic compound based on hydrazide pyrene skeleton, and preparation method and application thereof 万华化学集团股份有限公司 2024-12-20 CN claimed
CN-116023552-B Catalyst and catalyst system for olefin polymerization 中国石油化工股份有限公司 2024-12-06 CN claimed
CN-116076675-B Low-gel yolk liquid, preparation method and application 成都鸾翔凤集食品有限公司 2024-11-08 CN claimed
CN-116023553-B Catalyst component for olefin polymerization reaction, catalyst system and application 中国石油化工股份有限公司 2024-09-17 CN claimed
CN-117447326-B Method for catalyzing carbonylation esterification reaction by cobalt compound activated by synthesis gas 中国科学院兰州化学物理研究所 2024-08-27 CN claimed
CN-115736150-B Yolk liquid instant drink and preparation method thereof 成都鸾翔凤集食品有限公司 2024-07-16 CN claimed
CN-110637015-B Fanisole X receptor agonist and application thereof 奥加诺沃公司 2024-04-02 CN claimed
CN-117447326-A Method for catalyzing carbonylation esterification reaction by cobalt compound activated by synthesis gas 中国科学院兰州化学物理研究所 2024-01-26 CN claimed
EP-4308560-A1 PRO DRUGS OF PDE10 COMPOUNDS Merck Sharp & Dohme LLC (US) 2024-01-24 EP claimed
WO-1996007323-A1 SELECTIVE HERBICIDES BASED ON ARYL URACILS BAYER AKTIENGESELLSCHAFT (DE) 1996-03-14 WO claimed
EP-0554215-A2 Diacrylates and dimethacrylates CIBA-GEIGY AG (CH) 1993-08-04 EP claimed
US-4898939-A Process for preparing 2β-substituted-methylpenicillin derivatives TAIHO PHARMACEUTICAL CO., LTD. (JP) 1990-02-06 US claimed
CN-1037344-A Therapeutically active cyclic methylene-1, 2-dicarboxylic acid amides, process for their preparation and pharmaceutical compositions containing them GUIDOTTI & C SPA LABOR (IT) 1989-11-22 CN claimed
US-4816452-A ANTIBIOTICS BEECHAM GROUP P.L.C. (GB) 1989-03-28 US claimed
EP-0210815-A2 6-Beta-(alpha-etherified oxyimino)-acylamino penicillanic-acid derivatives, their preparation and use BEECHAM GROUP PLC (GB) 1987-02-04 EP claimed
US-4272511-A POLYMER OF VINYLPYRROLIDONE, VINYL ACETATE, CROTONIC ACID AND AT LEAST ONE OTHER MONOMER L'OREAL (FR) 1981-06-09 US claimed
US-4157435-A TITANIUM, ALUMINUM, SILOXANE COORDINATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1979-06-05 US claimed
US-4085276-A CATALYST COMPOSED OF AN ORGANOMETALLIC COMPOUND AND THE REACTION PRODUCT OF A MAGNESIUM COMPOUND AND A TITANIUM COMPOUND MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1978-04-18 US claimed
US-3963787-A PALLADIUM CARBOXYLATE CATALYST TEIJIN LIMITED (JA) 1976-06-15 US claimed