Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 0.85 |
| ▸ | CNR2 | P34972 | 8/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18547659 | 0.87 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL18547687 | 0.86 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL18548002 | 0.85 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL18547598 | 0.85 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL18547744 | 0.85 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL18547916 | 0.84 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL18547679 | 0.83 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL18547950 | 0.81 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL18547718 | 0.81 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL18547694 | 0.81 | CNR1 (1.00) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017034872-A1 | INDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-02 | — | — | WO | disclosed |