Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 18/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18554613 | 0.92 | CNR1 (0.44) | CNR1CNR2CYP2C19 | |
| SCHEMBL18547325 | 0.90 | CNR1 (0.56) | CNR1CNR2CYP2C19 | |
| SCHEMBL18554595 | 0.89 | CNR1 (0.43) | CNR1CNR2CYP2C19 | |
| SCHEMBL18554607 | 0.87 | CNR1 (0.46) | CNR1CNR2CYP2C19 | |
| SCHEMBL18554587 | 0.85 | CNR1 (0.43) | CNR1CNR2CYP2C19 | |
| SCHEMBL18547275 | 0.82 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL18546993 | 0.80 | CNR1 (0.56) | CNR1CNR2CYP2C19 | |
| SCHEMBL18547339 | 0.80 | CNR1 (0.55) | CNR1CNR2CYP2C19 | |
| SCHEMBL18547453 | 0.79 | CNR1 (0.55) | CNR1CNR2CYP2C19 | |
| SCHEMBL18547187 | 0.79 | CNR1 (0.55) | CNR1CNR2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017035114-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-02 | — | — | WO | disclosed |