Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18558524 | 0.93 | MEN1 (0.35) | CHEK1TRPV1MEN1ALDH1A1KMT2A | |
| SCHEMBL9920869 | 0.93 | NPC1 (0.42) | TAS1R3TAS1R1TAS1R2KCNH2DPP4 | |
| SCHEMBL9920911 | 0.93 | NPC1 (0.39) | TAS1R3TAS1R1TAS1R2KCNQ3KCNQ2 | |
| SCHEMBL9921132 | 0.90 | HDAC4 (0.40) | TAS1R3TAS1R1TAS1R2KCNQ3KCNQ2 | |
| SCHEMBL19362654 | 0.89 | TRPV1 (0.42) | CHEK1TRPV1KCNH2CCNA2CDK2 | |
| SCHEMBL9921119 | 0.86 | MAPK1 (0.39) | KCNH2NPC1RAB9AHDAC4HTR2B | |
| SCHEMBL9920822 | 0.85 | HDAC6 (0.36) | TRPV1MEN1ALDH1A1KMT2ACCNA2 | |
| SCHEMBL9920885 | 0.85 | ACKR3 (0.37) | MEN1ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL9921133 | 0.85 | GSK3B (0.39) | KCNH2NPC1RAB9ASMN1; SMN2HDAC4 | |
| SCHEMBL9921025 | 0.83 | HDAC6 (0.39) | TRPV1KCNH2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580388-B2 | Pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2017-02-28 | — | — | US | disclosed |