Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CHAT | P28329 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19649207 | 0.95 | BACE1 (0.43) | BACE1CHATAPPMAPTCTSB | |
| SCHEMBL14401515 | 0.87 | CYP1A1 (0.42) | BACE1CYP19A1MAPTCTSB | |
| SCHEMBL14401518 | 0.82 | CYP1A1 (0.40) | BACE1CYP19A1CHATMAPT | |
| SCHEMBL12451468 | 0.81 | KDM4A (0.43) | APPMAPT | |
| SCHEMBL16070280 | 0.78 | APP (0.32) | APP | |
| SCHEMBL10104183 | 0.78 | BACE1 (0.48) | BACE1CYP19A1CHATAPPMAPT | |
| SCHEMBL21005628 | 0.77 | — | — | |
| SCHEMBL18774215 | 0.75 | CHRM2 (0.31) | — | |
| SCHEMBL14802459 | 0.74 | BACE1 (0.45) | BACE1CYP19A1CHATAPPMAPT | |
| SCHEMBL21005805 | 0.74 | KDM4A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2781556-B1 | Method of colouring and lightening keratin materials in the presence of a reducing agent comprising a fluorescent disulphide dye | L'ORÉAL (FR) | 2017-03-01 | — | — | EP | disclosed |