SCHEMBL18564665

SCHEMBL18564665

CN(c1ccccc1)c1ccc(-c2ccc(-c3ccc4c5ccccc5n(-c5ccccc5)c4c3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
ATM Q13315 1/20 0.51
REN P00797 1/20 0.40
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
ALDH1A1 P00352 2/20 0.37
GFER P55789 1/20 0.37
HDAC4 P56524 1/20 0.37
AVPR1A P37288 1/20 0.36
CHKA P35790 2/20 0.35
PRMT5 O14744 1/20 0.35
MAT2A P31153 1/20 0.35
KMT2A Q03164 2/20 0.35
MAPK8 P45983 1/20 0.35
IL1R1 P14778 1/20 0.35
TSPO P30536 1/20 0.34
MAPT P10636 2/20 0.34
PGR P06401 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18564745 1.00 KDM4E (0.51) KDM4EL3MBTL1ATMRENRXRA
SCHEMBL19735350 0.97 KDM4E (0.51) KDM4EL3MBTL1ATMRENRXRA
SCHEMBL18564820 0.96 KDM4E (0.46) KDM4EL3MBTL1ATMRENRXRA
SCHEMBL18564765 0.96 KDM4E (0.46) KDM4EL3MBTL1ATMRENRXRA
SCHEMBL10052387 0.94 KDM4E (0.47) KDM4EL3MBTL1ATMRENRXRA
SCHEMBL18565070 0.93 KDM4E (0.47) KDM4EL3MBTL1ATMRENRXRA
SCHEMBL18564883 0.93 ATM (0.44) KDM4EL3MBTL1ATMRENRXRA
SCHEMBL18564889 0.93 ATM (0.44) KDM4EL3MBTL1ATMRENRXRA
SCHEMBL18564673 0.91 KDM4E (0.51) KDM4EL3MBTL1ATMRENRXRA
SCHEMBL18564671 0.91 KDM4E (0.51) KDM4EL3MBTL1ATMRENRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 KDM4E 225/4885L3MBTL1 1263/4885ATM 3092/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 KDM4E 225/4885L3MBTL1 1263/4885ATM 3092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.