⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1854396 | 0.97 | — | — | |
| SCHEMBL2021260 | 0.76 | — | — | |
| SCHEMBL400853 | 0.74 | — | — | |
| SCHEMBL29524134 | 0.74 | — | — | |
| SCHEMBL16701558 | 0.74 | — | — | |
| SCHEMBL23212103 | 0.74 | — | — | |
| SCHEMBL5419514 | 0.74 | — | — | |
| SCHEMBL401149 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL400450 | 0.72 | LOX (0.35) | — | |
| Hydrochloric Acid SCHEMBL29444594 | 0.72 | LOX (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325186-A2 | Fused Bicyclic mTor Inhibitors | OSI Pharmaceuticals, Inc. (US) | 2011-05-25 | — | — | EP | disclosed |
| EP-1981890-A2 | UNSATURATED mTOR INHIBITORS | OSI Pharmaceuticals, Inc. (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007087395-A2 | UNSATURATED mTOR INHIBITORS | OSI PHARMACEUTICALS, INC. (US) | 2007-08-02 | — | — | WO | disclosed |