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Sugi Predict / Compounds / SCHEMBL18565237

SCHEMBL18565237

SCHEMBL18565237

c1ccc(N(c2ccc(-c3cc(-c4ccc(N(c5ccccc5)c5ccc6c7ccccc7n(-c7ccccc7)c6c5)cc4)nc(-c4ccc(N(c5ccccc5)c5ccc6c7ccccc7n(-c7ccccc7)c6c5)cc4)n3)cc2)c2ccc3c4ccccc4n(-c4ccccc4)c3c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 6/20 0.44
▸ ATM Q13315 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ MEN1 O00255 7/20 0.38
▸ KMT2A Q03164 7/20 0.38
▸ MAPT P10636 7/20 0.38
▸ ALDH1A1 P00352 6/20 0.38
▸ HPGD P15428 6/20 0.38
▸ NTSR1 P30989 1/20 0.38
▸ LMNA P02545 2/20 0.35
▸ GLA P06280 2/20 0.35
▸ PTGER4 P35408 1/20 0.34
▸ CYP2C19 P33261 3/20 0.34
▸ CYP1A2 P05177 3/20 0.34
▸ CYP3A4 P08684 2/20 0.34
▸ CYP2D6 P10635 2/20 0.34
▸ TSHR P16473 2/20 0.34
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565226 0.98 KDM4E (0.41) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL18565245 0.94 KDM4E (0.43) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL18565242 0.94 KDM4E (0.47) KDM4EATML3MBTL1KMT2AMAPT
SCHEMBL18565234 0.93 KDM4E (0.44) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL18565231 0.91 KDM4E (0.44) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL18565244 0.91 KDM4E (0.42) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL18565217 0.90 KDM4E (0.41) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL18566377 0.90 KDM4E (0.41) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL18566374 0.90 KDM4E (0.41) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL18566371 0.90 KDM4E (0.41) KDM4EATML3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 KDM4E 225/4885ATM 3092/4885L3MBTL1 1263/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 KDM4E 225/4885ATM 3092/4885L3MBTL1 1263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.