Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185246 | 0.84 | BUB1 (0.42) | CCR4 | |
| SCHEMBL185344 | 0.84 | CCR4 (0.43) | CCR4 | |
| SCHEMBL186059 | 0.83 | CCR4 (0.51) | CCR4 | |
| SCHEMBL186961 | 0.82 | CCR4 (0.44) | CCR4 | |
| SCHEMBL185375 | 0.82 | CCR4 (0.43) | CCR4 | |
| SCHEMBL186309 | 0.81 | CCR4 (0.49) | CCR4GAA | |
| SCHEMBL186057 | 0.79 | CCR4 (0.49) | CCR4 | |
| SCHEMBL185658 | 0.76 | CCR4 (0.58) | CCR4 | |
| SCHEMBL186311 | 0.74 | GRIN1 (0.42) | CCR4 | |
| SCHEMBL358265 | 0.71 | CCR4 (0.78) | CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401270-A1 | PYRAZOLE DERIVATIVES USED AS CCR4 RECEPTOR ANTAGONISTS | Glaxo Group Limited (GB) | 2012-01-04 | — | — | EP | disclosed |