Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 14/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13467261 | 0.88 | BACE1 (0.39) | BACE1 | |
| SCHEMBL13466086 | 0.88 | BACE1 (0.39) | BACE1 | |
| SCHEMBL15693452 | 0.86 | BACE1 (0.56) | BACE1 | |
| SCHEMBL13467260 | 0.86 | BACE1 (0.56) | BACE1 | |
| SCHEMBL13466988 | 0.78 | BACE1 (0.41) | BACE1 | |
| SCHEMBL13467022 | 0.78 | BACE1 (0.49) | BACE1 | |
| SCHEMBL18567433 | 0.78 | BACE1 (0.49) | BACE1 | |
| SCHEMBL13466955 | 0.76 | BACE1 (0.62) | BACE1 | |
| SCHEMBL17325999 | 0.74 | BACE1 (0.64) | BACE1 | |
| SCHEMBL13466614 | 0.74 | BACE1 (0.64) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697210-B1 | 5-SUBSTITUTED IMINOTHIAZINES AND THEIR MONO-AND DIOXIDES AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE | MERCK SHARP & DOHME (US) | 2017-03-01 | — | — | EP | disclosed |