Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12885610 | 0.89 | KDM4E (0.33) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL1225992 | 0.82 | KDM4E (0.32) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL10199736 | 0.79 | PDE4A (0.32) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL18568160 | 0.77 | KDM4E (0.32) | KDM4E | |
| SCHEMBL10199684 | 0.75 | PDE4A (0.33) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL18567693 | 0.73 | HTR2A (0.33) | KDM4EHPGDNR2F2 | |
| SCHEMBL16994205 | 0.71 | TAAR1 (0.31) | — | |
| SCHEMBL13002855 | 0.71 | NPC1 (0.34) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10127468 | 0.71 | — | — | |
| SCHEMBL16994580 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334175-B1 | PHENYL-SUBSTITUTED BICYCLOOCTANE 1,3 DIONE DERIVATIVES | BAYER IP GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |