Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18567822 | 0.85 | BACE1 (0.51) | BACE1BACE2 | |
| SCHEMBL18567381 | 0.82 | BACE1 (0.41) | BACE1BACE2 | |
| SCHEMBL18567394 | 0.82 | BACE1 (0.46) | BACE1BACE2 | |
| SCHEMBL13466605 | 0.78 | BACE1 (0.60) | BACE1BACE2 | |
| SCHEMBL18567947 | 0.77 | BACE1 (0.48) | BACE1BACE2 | |
| SCHEMBL18567406 | 0.77 | BACE1 (0.49) | BACE1BACE2 | |
| SCHEMBL18567273 | 0.77 | BACE1 (0.46) | BACE1BACE2 | |
| SCHEMBL18567787 | 0.75 | BACE1 (0.51) | BACE1 | |
| SCHEMBL18567390 | 0.75 | BACE1 (0.49) | BACE1BACE2 | |
| SCHEMBL18567401 | 0.74 | BACE1 (0.50) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697210-B1 | 5-SUBSTITUTED IMINOTHIAZINES AND THEIR MONO-AND DIOXIDES AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE | MERCK SHARP & DOHME (US) | 2017-03-01 | — | — | EP | disclosed |