Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927818 | 0.79 | HPGD (0.56) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL2701014 | 0.79 | HDAC6 (0.59) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL25339470 | 0.76 | HDAC1 (0.53) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL6864627 | 0.75 | NPC1 (0.47) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL1404052 | 0.75 | HDAC1 (0.46) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL251078 | 0.74 | HDAC1 (0.44) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL1403726 | 0.74 | TNKS (0.53) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL18568508 | 0.74 | GRM5 (0.55) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL1974224 | 0.72 | — | — | |
| SCHEMBL3436865 | 0.72 | HDAC3 (0.61) | HDAC1HDAC8HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585451-B1 | HETEROCYCLIC COMPOUNDS AS AGENTS FOR PEST CONTROL | BAYER IP GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |