Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402341 | 0.97 | HPGD (0.42) | PDK2HPGDESR1ESR2ELANE | |
| SCHEMBL4401218 | 0.97 | PDK2 (0.43) | PDK2HPGDESR1ESR2ELANE | |
| SCHEMBL4400942 | 0.97 | HPGD (0.42) | PDK2HPGDESR1ESR2ELANE | |
| SCHEMBL20198263 | 0.97 | HPGD (0.42) | PDK2HPGDESR1ESR2ELANE | |
| SCHEMBL20198238 | 0.97 | HPGD (0.42) | PDK2HPGDESR1ESR2ELANE | |
| SCHEMBL20198220 | 0.93 | PDK2 (0.42) | PDK2HPGDESR1ESR2ELANE | |
| SCHEMBL12336787 | 0.93 | PDK2 (0.42) | PDK2HPGDESR1ESR2ELANE | |
| SCHEMBL4402995 | 0.93 | PDK2 (0.42) | PDK2HPGDESR1ESR2ELANE | |
| SCHEMBL4401118 | 0.93 | PDK2 (0.42) | PDK2HPGDESR1ESR2ELANE | |
| SCHEMBL20198278 | 0.93 | PDK2 (0.42) | PDK2HPGDESR1ESR2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888706-B1 | ORGANIC ELECTROLUMINESCENT DEVICE AND BORIC ACID AND BORINIC ACID DERIVATIVES USED THEREIN | MERCK PATENT GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |