Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103942 | 0.81 | PIK3R1 (0.30) | — | |
| SCHEMBL9107618 | 0.81 | AR (0.30) | — | |
| SCHEMBL9103934 | 0.81 | PIK3R1 (0.30) | — | |
| SCHEMBL9104643 | 0.81 | PIK3R1 (0.30) | — | |
| SCHEMBL932638 | 0.81 | AR (0.30) | — | |
| SCHEMBL932232 | 0.81 | AR (0.30) | — | |
| SCHEMBL9108318 | 0.74 | PIK3CA (0.43) | — | |
| SCHEMBL931809 | 0.74 | PIK3CA (0.43) | — | |
| SCHEMBL9106512 | 0.74 | PIK3CA (0.43) | — | |
| SCHEMBL16271110 | 0.72 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448939-B1 | 2,3-DIHYDRO-1H-IMIDAZO {1,2-A} PYRIMIDIN-5-ONE DERIVATIVES, THE PREPARATION AND PHARMACEUTICAL USE THEREOF | SANOFI SA (FR) | 2017-03-01 | — | — | EP | disclosed |