Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4905931 | 0.87 | MDM2 (0.84) | MDM2TP53 | |
| SCHEMBL4905939 | 0.87 | MDM2 (0.84) | MDM2TP53 | |
| SCHEMBL18569188 | 0.86 | MDM2 (0.82) | MDM2TP53 | |
| SCHEMBL4915381 | 0.85 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL4915376 | 0.85 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL4914047 | 0.81 | MDM2 (0.68) | MDM2TP53 | |
| SCHEMBL4914049 | 0.81 | MDM2 (0.68) | MDM2TP53 | |
| SCHEMBL8273745 | 0.77 | MDM2 (0.73) | MDM2TP53 | |
| SCHEMBL4914808 | 0.76 | MDM2 (0.69) | MDM2TP53 | |
| SCHEMBL4914805 | 0.76 | MDM2 (0.69) | MDM2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786773-B1 | ISOINDOLIN-1-ONE DERIVATIVES | CANCER RES TECH LTD (GB) | 2017-03-01 | — | — | EP | disclosed |