Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 18/20 | 0.69 |
| ▸ | NMT2 | O60551 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16509623 | 0.84 | NMT1 (0.78) | NMT1NMT2KCNH2 | |
| SCHEMBL16509526 | 0.83 | NMT1 (0.74) | NMT1NMT2KCNH2 | |
| SCHEMBL16503058 | 0.81 | NMT1 (1.00) | NMT1NMT2KCNH2 | |
| SCHEMBL16503009 | 0.80 | NMT1 (0.61) | NMT1NMT2KCNH2L3MBTL1 | |
| SCHEMBL1852757 | 0.79 | NMT1 (0.71) | NMT1NMT2KCNH2L3MBTL1 | |
| SCHEMBL16503006 | 0.79 | NMT1 (0.67) | NMT1NMT2KCNH2L3MBTL1 | |
| SCHEMBL1849838 | 0.79 | NMT1 (1.00) | NMT1L3MBTL1 | |
| SCHEMBL16503065 | 0.78 | NMT1 (1.00) | NMT1NMT2KCNH2 | |
| SCHEMBL16503056 | 0.78 | NMT1 (0.85) | NMT1NMT2KCNH2 | |
| SCHEMBL16503052 | 0.78 | NMT1 (0.75) | NMT1NMT2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323987-A1 | N-MYRISTOYL TRANSFERASE INHIBITORS | University of Dundee (GB) | 2011-05-25 | — | — | EP | disclosed |