SCHEMBL18570211

SCHEMBL18570211

CCNCC(C)(C)CN(C)C=O

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4667733 0.78 TP53 (0.33)
SCHEMBL271154 0.78 USP2 (0.34) USP2ALOX15
SCHEMBL11509107 0.71 TP53 (0.47)
SCHEMBL271361 0.69
SCHEMBL15056850 0.66
SCHEMBL2108684 0.66 USP2 (0.36) USP2ALOX15
SCHEMBL1831649 0.64
Diethylamine SCHEMBL8308118 0.63 TSHR (0.60) USP2ALOX15
SCHEMBL24920832 0.62 TP53 (0.37)
SCHEMBL16293553 0.62 TP53 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2948434-B1 SQUARIC DERIVATIVES FOR THE TREATMENT OF HEPATITIS C BRISTOL MYERS SQUIBB CO (US) 2017-03-01 EP disclosed