Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDA | P32320 | 12/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587511 | 1.00 | CDA (1.00) | CDAPDE4DPDE3ASLC29A1 | |
| SCHEMBL13030857 | 1.00 | CDA (1.00) | CDAPDE4DPDE3ASLC29A1 | |
| SCHEMBL586883 | 1.00 | CDA (1.00) | CDAPDE4DPDE3ASLC29A1 | |
| SCHEMBL13145227 | 0.86 | CDA (0.75) | CDAPDE4DPDE3ASLC29A1 | |
| SCHEMBL14931007 | 0.80 | CDA (0.67) | CDAPDE4DPDE3ASLC29A1 | |
| SCHEMBL13030835 | 0.79 | CDA (0.65) | CDAPDE4DPDE3ASLC29A1 | |
| SCHEMBL23227176 | 0.78 | CDA (0.67) | CDAPDE4DPDE3ASLC29A1 | |
| SCHEMBL171923 | 0.78 | CDA (0.67) | CDAPDE4DPDE3ASLC29A1 | |
| SCHEMBL20788791 | 0.78 | CDA (0.67) | CDAPDE4DPDE3ASLC29A1 | |
| SCHEMBL23467212 | 0.78 | CDA (0.67) | CDAPDE4DPDE3ASLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2416780-B1 | COMBINATION OF DECITABINE WITH CYTIDINE DEAMINASE INHIBITOR AND USE THEREOF IN THE TREATMENT OF CANCER | OTSUKA PHARMA CO LTD (JP) | 2017-03-08 | — | — | EP | disclosed |
| EP-2416781-B1 | COMBINATION OF CYTIDINE-BASED ANTINEOPLASTIC DRUGS WITH CYTIDINE DEAMINASE INHIBITOR AND USE THEREOF IN THE TREATMENT OF CANCER | OTSUKA PHARMA CO LTD (JP) | 2017-03-08 | — | — | EP | disclosed |
| EP-2416781-B1 | COMBINATION OF CYTIDINE-BASED ANTINEOPLASTIC DRUGS WITH CYTIDINE DEAMINASE INHIBITOR AND USE THEREOF IN THE TREATMENT OF CANCER | OTSUKA PHARMA CO LTD (JP) | 2017-03-08 | — | — | EP | disclosed |