Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 16/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18547178 | 0.82 | SOS1 (0.44) | CNR1SOS1CNR2MCHR1 | |
| SCHEMBL18547007 | 0.81 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL18547535 | 0.81 | NPC1 (0.38) | SOS1MCHR1 | |
| SCHEMBL18547397 | 0.79 | JAK2 (0.46) | CNR1MCHR1 | |
| SCHEMBL18547282 | 0.78 | NPC1 (0.38) | SOS1MCHR1 | |
| SCHEMBL18562587 | 0.77 | CNR1 (0.48) | CNR1SOS1CNR2MCHR1 | |
| SCHEMBL18546978 | 0.77 | CYP11B1 (0.41) | CNR1SOS1CNR2 | |
| Hydrochloric Acid SCHEMBL18546996 | 0.76 | CNR1 (0.47) | CNR1SOS1CNR2MCHR1 | |
| SCHEMBL18547059 | 0.75 | JAK2 (0.47) | CNR1MCHR1 | |
| SCHEMBL18547113 | 0.75 | PRCP (0.41) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017035114-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-02 | — | — | WO | disclosed |