SCHEMBL185769

SCHEMBL185769

FC(F)(F)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
LMNA P02545 1/20 0.46
CYP2D6 P10635 1/20 0.46
CALM1 P0DP23 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
HIF1A Q16665 1/20 0.44
CES1 P23141 1/20 0.44
FDPS P14324 1/20 0.43
EPHX2 P34913 1/20 0.42
TSHR P16473 4/20 0.41
ALDH1A1 P00352 2/20 0.41
TRPA1 O75762 2/20 0.41
IDO1 P14902 1/20 0.41
TP53 P04637 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
MAOA P21397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29253660 0.97 SLC6A2 (0.48) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL29076224 0.95 SLC6A2 (0.46) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL19100363 0.86 SMN1; SMN2 (0.45) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL15959778 0.85 TAAR1 (0.50) SLC6A2TAAR1CYP1A2LMNATSHR
SCHEMBL7670360 0.84 ESR1 (0.38) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL19224281 0.82 SLC6A2 (0.50) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL5211703 0.80 SLC6A2 (0.48) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL22262625 0.79 NR1H2 (0.58) TAAR1CYP1A2CYP2C19LMNACYP2D6
SCHEMBL8002017 0.78 SLC6A2 (0.58) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL5610133 0.78 CES1 (0.46) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 805 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024366-B Preparation method of dihydropyrazole compound containing quaternary carbon center 安徽中医药大学 2025-05-02 CN claimed
CN-119263967-A Chiral cis-cyclobutane derivative and method for preparing same by taking weak polarized olefin as substrate 华侨大学 2025-01-07 CN claimed
CN-117024366-A Preparation method of dihydropyrazole compound containing quaternary carbon center 安徽中医药大学 2023-11-10 CN claimed
EP-4185564-A1 TRICYCLIC HETEROCYCLES Merck Patent GmbH (DE) 2023-05-31 EP claimed
WO-2023078813-A1 HETEROBIFUNCTIONAL MOLECULES AS TEAD INHIBITORS MERCK PATENT GMBH (DE) 2023-05-11 WO claimed
CN-114583088-A Quantum dot light-emitting diode and preparation method thereof TCL科技集团股份有限公司 2022-06-03 CN claimed
WO-2022111583-A1 QUANTUM DOT LIGHT-EMITTING DIODE AND PREPARATION METHOD THEREFOR TCL科技集团股份有限公司 2022-06-02 WO claimed
CN-109651396-B Alkylation of alkyl fluoroalkylsulfonates 诺华股份有限公司 2021-09-14 CN claimed
EP-3774813-A1 PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST BeiGene, Ltd. (KY) 2021-02-17 EP claimed
CN-111954571-A Poly (arylpiperidinium) polymers including those having stable cationic side groups for use as anion exchange membranes and ionomers 特拉华大学 2020-11-17 CN claimed
US-4962183-A HEAT, OXIDATION AND SOLVENT RESISTANCE; MOLDING MATERIALS; MELT PROCESSIBILITY; FIBERS, FILMS AND SHEETS HOECHST CELANESE CORP. (US) 1990-10-09 US claimed
EP-0388657-A1 Polyamide-imide polymers having 12-F fluorine-containing linking groups HOECHST CELANESE CORPORATION (US) 1990-09-26 EP claimed
EP-0385303-A1 Shaped articles from polyamide-imide polymers having fluorine-containing linking groups HOECHST CELANESE CORPORATION (US) 1990-09-05 EP claimed
EP-0385304-A1 Polyamide-imide polymers having fluorine-containing linking groups HOECHST CELANESE CORPORATION (US) 1990-09-05 EP claimed
EP-0385305-A1 Polyamide-imide polymers having fluorine-containing linking groups HOECHST CELANESE CORPORATION (US) 1990-09-05 EP claimed
US-4954610-A SOLVENT, HEAT, OXIDATION, AND CHEMICAL RESISTANCE HOECHST CELANESE CORP. (US) 1990-09-04 US claimed
US-4954611-A Shaped articles from polyamide-imide polymers having fluorine containing linking groups HOECHST CELANESE CORP. (US) 1990-09-04 US claimed
US-4923960-A FIBERS, FILMS, SHEETS, MOLDINGS HOECHST CELANESE CORP. (US) 1990-05-08 US claimed
US-4849557-A Preparation of trifluoromethyltoluene from halomethylbenzotrifluoride CENTRAL GLASS COMPANY, LIMITED (JP) 1989-07-18 US claimed
EP-0034731-B1 TRIFLUOROMETHYLBENZYLIC ESTERS, THEIR INTERMEDIATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES BAYER AG (DE) 1985-10-30 EP claimed