⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24051077 | 0.63 | — | — | |
| SCHEMBL28261315 | 0.62 | CXCR2 (0.33) | — | |
| SCHEMBL28543569 | 0.61 | — | — | |
| SCHEMBL17970624 | 0.61 | — | — | |
| SCHEMBL4324998 | 0.61 | HTR2A (0.36) | — | |
| SCHEMBL24027196 | 0.60 | SMN1; SMN2 (0.34) | — | |
| Chloromethane SCHEMBL28145551 | 0.59 | — | — | |
| SCHEMBL25514337 | 0.59 | — | — | |
| SCHEMBL19557899 | 0.59 | — | — | |
| SCHEMBL9773765 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868994-B1 | SULFONYLPYRROLES AS HISTONE DEACETYLASE INHIBITORS | 4SC AG (DE) | 2011-05-25 | — | — | EP | disclosed |
| US-20090117074-A1 | Sulfonylpyrroles as Histone Deacetylase Inhibitors | NYCOMED GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
| EP-1868994-A1 | SULFONYLPYRROLES AS HISTONE DEACETYLASE INHIBITORS | Nycomed GmbH (DE) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006105979-A1 | SULFONYLPYRROLES AS HISTONE DEACETYLASE INHIBITORS | NYCOMED GMBH (DE) | 2006-10-12 | — | — | WO | disclosed |