Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | DDO | Q99489 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | TPMT | P51580 | 1/20 | 0.56 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29586507 | 1.00 | HCAR2 (1.00) | HCAR2ATMALDH1A1KDM4EMEN1 | |
| SCHEMBL28807541 | 1.00 | HCAR2 (1.00) | HCAR2ATMALDH1A1KDM4EMEN1 | |
| Ammonia Solution, Strong SCHEMBL27341465 | 0.98 | HCAR2 (0.96) | HCAR2ATMALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL1374255 | 0.98 | HCAR2 (0.96) | HCAR2ATMALDH1A1KDM4EMEN1 | |
| SCHEMBL9507781 | 0.98 | HCAR2 (0.96) | HCAR2ATMALDH1A1KDM4EMEN1 | |
| Methyl Alcohol SCHEMBL28625386 | 0.98 | HCAR2 (0.96) | HCAR2ATMALDH1A1KDM4EMEN1 | |
| Formaldehyde SCHEMBL27662616 | 0.96 | HCAR2 (0.92) | HCAR2ATMALDH1A1KDM4EMEN1 | |
| Hydrazine SCHEMBL28220034 | 0.96 | HCAR2 (0.92) | HCAR2ATMALDH1A1KDM4EMEN1 | |
| Methylene Chloride SCHEMBL28328829 | 0.92 | HCAR2 (0.85) | HCAR2ATMALDH1A1KDM4EMEN1 | |
| SCHEMBL51830 | 0.83 | HCAR2 (0.70) | HCAR2ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 889 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462646-A | Substituted tetrahydro-beta-carboline derivative, synthesis method and application thereof | 江苏科技大学 | 2025-02-18 | — | — | CN | claimed |
| US-20250017954-A1 | Formulations and Methods for Treating Symptoms of Menopause | Kindra Corporation (US) | 2025-01-16 | — | — | US | claimed |
| CN-118908817-A | Synthesis method of 2,2' - (benzylidene) bis (3-hydroxy-5, 5-dimethylcyclohex-2-en-1-one) compound | 宁夏师范学院 | 2024-11-08 | — | — | CN | claimed |
| CN-118851997-A | Purification method of 5-methylnicotinic acid | 浙江博迈科生物医药研发有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118510501-A | Formulations and methods for treating climacteric symptoms | 金卓拉公司 | 2024-08-16 | — | — | CN | claimed |
| CN-118206532-A | Preparation method of rupatadine fumarate and rupatadine fumarate | 广东九明制药有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-118047783-A | Substituted triazole compound and preparation method and application thereof | 山东大学 | 2024-05-17 | — | — | CN | claimed |
| CN-114998621-B | SERS quantitative analysis method based on coffee ring concentration effect and image processing technology | 嘉兴学院 | 2024-04-16 | — | — | CN | claimed |
| CN-117720458-A | Preparation method of rupatadine intermediate 5-methyl-3-pyridine methanol | 北京嘉林药业股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117417291-A | Preparation method of rupatadine fumarate intermediate 5-methyl-3-hydroxymethylpyridine | 北京嘉林药业股份有限公司 | 2024-01-19 | — | — | CN | claimed |
| WO-2002018366-A1 | PROCESS FOR THE SYNTHESIS OF N-(5-METHYLNICOTINOYL)-4-HYDROXYPIPERIDINE, A KEY INTERMEDIATE OF RUPATADINE | RANBAXY LABORATORIES LIMITED (IN) | 2002-03-07 | — | — | WO | claimed |
| EP-0577957-B1 | 8-Chloro-11-[1-[(5-methyl-3-pyridyl)methyl]-4-piperidyliden]-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine | URIACH & CIA SA J (ES) | 1995-07-12 | — | — | EP | claimed |
| EP-0577957-A1 | 8-Chloro-11-[1-[(5-methyl-3-pyridyl)methyl]-4-piperidyliden]-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine | J. URIACH & CIA. S.A. (ES) | 1994-01-12 | — | — | EP | claimed |
| EP-0272903-B1 | PROCESS FOR PRODUCING A POLYARYLENE SULFIDE | Tosoh Corporation (JP) | 1993-07-21 | — | — | EP | claimed |
| CN-1067653-A | Novel herbicide | RHONE POULENC AGRICULTURE (GB) | 1993-01-06 | — | — | CN | claimed |
| EP-0159769-B1 | ELECTROCHEMICAL OXIDATION OF PYRIDINE BASES | REILLY INDUSTRIES, INC. (US) | 1991-03-27 | — | — | EP | claimed |
| EP-0159769-A1 | Electrochemical oxidation of pyridine bases | REILLY INDUSTRIES, INC. (US) | 1985-10-30 | — | — | EP | claimed |
| EP-0044931-B1 | 2-0 AND 5-0-SUBSTITUTED 1,4;3,6-DIANHYDRO-HEXITE MONONITRATES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS | Dr. Willmar Schwabe GmbH & Co. (DE) | 1985-04-10 | — | — | EP | claimed |
| US-4482439-A | Electrochemical oxidation of pyridine bases | REILLY TAR & CHEMICAL CORP. (US) | 1984-11-13 | — | — | US | claimed |
| US-4364953-A | CORONARY DISEASE | FIRMA WILLMAR SCHWABE (DE) | 1982-12-21 | — | — | US | claimed |