Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 5/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 5/20 | 0.43 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | STK25 | O00506 | 1/20 | 0.33 |
| ▸ | CIT | O14578 | 1/20 | 0.33 |
| ▸ | RIOK3 | O14730 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13657928 | 0.87 | BRD4 (0.48) | BRD4NTRK1NTRK3NTRK2SMN1; SMN2 | |
| SCHEMBL15743897 | 0.78 | BRD4 (0.48) | BRD4NTRK1NTRK3NTRK2SMN1; SMN2 | |
| SCHEMBL18307127 | 0.77 | BRD4 (0.47) | BRD4NTRK1NTRK3NTRK2SMN1; SMN2 | |
| SCHEMBL755912 | 0.77 | BRD4 (0.47) | BRD4NTRK1NTRK3NTRK2SMN1; SMN2 | |
| SCHEMBL13181117 | 0.77 | BRD4 (0.47) | BRD4NTRK1NTRK3NTRK2SMN1; SMN2 | |
| SCHEMBL16941382 | 0.75 | BRD4 (0.46) | BRD4NTRK1NTRK3NTRK2SMN1; SMN2 | |
| SCHEMBL13661740 | 0.75 | BRD4 (0.46) | BRD4NTRK1NTRK3NTRK2SMN1; SMN2 | |
| SCHEMBL18581246 | 0.73 | KDM4E (0.34) | AGBL2SMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL17026919 | 0.73 | BRD4 (0.48) | BRD4SMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL18581260 | 0.71 | BRD4 (0.41) | BRD4SMN1; SMN2ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170066717-A1 | NEW PHENYLAZETIDINECARBOXYLATE OR -CARBOXAMIDE COMPOUNDS | INVENTIVA (FR) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170066717-A1 | NEW PHENYLAZETIDINECARBOXYLATE OR -CARBOXAMIDE COMPOUNDS | NCOR1, NCOR2, NCOA1 | BRD4 120/4885NTRK1 254/4885NTRK3 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.