Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 5/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18585300 | 1.00 | PDE4A (0.58) | PDE4ATDP1USP2SLCO1B1LMNA | |
| SCHEMBL5703642 | 0.98 | PDE4A (0.60) | PDE4ATDP1USP2SLCO1B1LMNA | |
| SCHEMBL2256434 | 0.93 | PDE4A (0.54) | PDE4ATDP1USP2SLCO1B1LMNA | |
| SCHEMBL14643178 | 0.83 | OR51E2 (0.57) | PDE4ATDP1USP2SLCO1B1LMNA | |
| SCHEMBL3776284 | 0.83 | OR51E2 (0.57) | PDE4ATDP1USP2SLCO1B1LMNA | |
| SCHEMBL6839428 | 0.83 | OR51E2 (0.57) | PDE4ATDP1USP2SLCO1B1LMNA | |
| SCHEMBL640339 | 0.83 | OR51E2 (0.57) | PDE4ATDP1USP2SLCO1B1LMNA | |
| SCHEMBL6838462 | 0.83 | OR51E2 (0.57) | PDE4ATDP1USP2SLCO1B1LMNA | |
| SCHEMBL13062508 | 0.83 | OR51E2 (0.57) | PDE4ATDP1USP2SLCO1B1LMNA | |
| SCHEMBL13015306 | 0.83 | OR51E2 (0.57) | PDE4ATDP1USP2SLCO1B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180243309-A1 | TOPICAL ANTIVIRAL COMPOSITIONS | TOPICAL REMEDY LLC (US) | 2018-08-30 | — | — | US | disclosed |
| EP-3344265-A1 | TOPICAL ANTIVIRAL COMPOSITIONS | Topical Remedy, LLC (US) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017040844-A1 | TOPICAL ANTIVIRAL COMPOSITIONS | TOPICAL REMEDY, LLC (US) | 2017-03-09 | — | — | WO | disclosed |