Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.84 |
| ▸ | GLB1 | P16278 | 1/20 | 0.69 |
| ▸ | GBA1 | P04062 | 8/20 | 0.68 |
| ▸ | EBP | Q15125 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | GBA2 | Q9HCG7 | 9/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28637415 | 1.00 | GUSB (0.84) | GUSBGLB1GBA1EBPSIGMAR1 | |
| SCHEMBL15599059 | 0.91 | GUSB (0.92) | GUSBGLB1GBA1EBPSIGMAR1 | |
| SCHEMBL2268517 | 0.91 | GUSB (1.00) | GUSBGLB1GBA1GBA2GAA | |
| SCHEMBL2430985 | 0.91 | GUSB (0.92) | GUSBGLB1GBA1EBPSIGMAR1 | |
| SCHEMBL2430986 | 0.91 | GUSB (0.92) | GUSBGLB1GBA1EBPSIGMAR1 | |
| SCHEMBL1857461 | 0.91 | GUSB (1.00) | GUSBGLB1GBA1GBA2GAA | |
| SCHEMBL15599026 | 0.91 | GUSB (0.92) | GUSBGLB1GBA1EBPSIGMAR1 | |
| SCHEMBL15599058 | 0.91 | GUSB (0.92) | GUSBGLB1GBA1EBPSIGMAR1 | |
| SCHEMBL2435897 | 0.91 | GUSB (0.92) | GUSBGLB1GBA1EBPSIGMAR1 | |
| SCHEMBL3378221 | 0.91 | GUSB (0.92) | GUSBGLB1GBA1EBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323651-A2 | COMPOUNDS FOR THE TREATMENT OF FLAVIVIRAL INFECTIONS | Summit Corporation Plc (GB) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010029313-A1 | ANTIINFECTIVE COMPOUNDS | SUMMIT CORPORATION PLC. (GB) | 2010-03-18 | — | — | WO | disclosed |
| WO-2010015815-A2 | COMPOUNDS FOR THE TREATMENT OF FLAVIVIRAL INFECTIONS | SUMMIT CORPORATION PLC (GB) | 2010-02-11 | — | — | WO | disclosed |