Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.53 |
| ▸ | GRK5 | P34947 | 1/20 | 0.53 |
| ▸ | CDK8 | P49336 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17034162 | 0.84 | CYP11B1 (0.52) | S1PR5S1PR1GRK5CDK8NOTUM | |
| SCHEMBL17027210 | 0.82 | S1PR5 (0.53) | S1PR5S1PR1NOTUMPRKXIKBKE | |
| SCHEMBL17026911 | 0.82 | NOTUM (0.58) | S1PR5S1PR1GRK5CDK8NOTUM | |
| SCHEMBL17034087 | 0.80 | NOTUM (0.68) | S1PR5S1PR1GRK5CDK8NOTUM | |
| SCHEMBL17034177 | 0.78 | NOTUM (0.51) | S1PR5S1PR1NOTUMALDH1A1MAPT | |
| SCHEMBL17034161 | 0.77 | S1PR5 (0.49) | S1PR5S1PR1NOTUMPDGFRAPIM1 | |
| SCHEMBL17034174 | 0.76 | S1PR5 (0.55) | S1PR5S1PR1NOTUMPRKXIKBKE | |
| SCHEMBL17027029 | 0.76 | PTGDR2 (0.49) | S1PR5S1PR1NOTUMPDGFRA | |
| SCHEMBL17034083 | 0.76 | S1PR5 (0.53) | S1PR5S1PR1NOTUMPRKXIKBKE | |
| SCHEMBL17027148 | 0.75 | PTGDR2 (0.53) | S1PR5S1PR1NOTUMSMN1; SMN2PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170066717-A1 | NEW PHENYLAZETIDINECARBOXYLATE OR -CARBOXAMIDE COMPOUNDS | INVENTIVA (FR) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170066717-A1 | NEW PHENYLAZETIDINECARBOXYLATE OR -CARBOXAMIDE COMPOUNDS | NCOR1, NCOR2, NCOA1 | S1PR5 2041/4885S1PR1 1142/4885GRK5 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.