Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16750016 | 0.93 | SYK (0.71) | SYK | |
| SCHEMBL16840116 | 0.84 | SYK (0.61) | SYK | |
| SCHEMBL16876078 | 0.84 | SYK (0.58) | SYK | |
| SCHEMBL1982466 | 0.84 | SYK (0.61) | SYK | |
| SCHEMBL15570980 | 0.83 | SYK (1.00) | SYK | |
| SCHEMBL19664622 | 0.83 | SYK (0.72) | SYK | |
| SCHEMBL17006567 | 0.81 | SYK (1.00) | SYK | |
| SCHEMBL16750012 | 0.81 | SYK (0.70) | SYK | |
| SCHEMBL19575362 | 0.81 | SYK (0.85) | SYK | |
| SCHEMBL16964968 | 0.81 | SYK (0.60) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586931-B2 | Triazolyl derivatives as Syk inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-03-07 | — | — | US | disclosed |