Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16545981 | 0.92 | SPHK1 (0.49) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL10211186 | 0.92 | SPHK1 (0.49) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL17819877 | 0.92 | SPHK1 (0.49) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL7305261 | 0.87 | SPHK1 (0.49) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL6208002 | 0.87 | SPHK1 (0.49) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL16071281 | 0.87 | SPHK1 (0.58) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL6208006 | 0.87 | SPHK1 (0.49) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL15925996 | 0.86 | SPHK1 (0.48) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL13455766 | 0.86 | SPHK1 (0.48) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL18959562 | 0.86 | SPHK1 (0.60) | SPHK1HSD11B2BRD4HCRTR2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |