Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | FABP6 | P51161 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12724845 | 0.85 | KDM4E (0.62) | KDM4EHSD17B10LMNACYP1A2FABP6 | |
| SCHEMBL5989926 | 0.79 | KDM4E (0.56) | KDM4EHSD17B10LMNACYP1A2FABP6 | |
| SCHEMBL12938095 | 0.79 | KDM4E (0.69) | KDM4EHSD17B10LMNACYP1A2MEN1 | |
| SCHEMBL20643778 | 0.79 | KDM4E (0.51) | KDM4EHSD17B10LMNACYP1A2ALDH1A1 | |
| SCHEMBL16599647 | 0.76 | KDM4E (0.56) | KDM4EHSD17B10LMNACYP1A2FABP6 | |
| SCHEMBL5990707 | 0.76 | KDM4E (0.56) | KDM4EHSD17B10LMNACYP1A2FABP6 | |
| SCHEMBL17300677 | 0.76 | HSD17B10 (0.56) | KDM4EHSD17B10LMNACYP1A2FABP6 | |
| SCHEMBL13542756 | 0.76 | KDM4E (0.56) | KDM4EHSD17B10LMNACYP1A2FABP6 | |
| SCHEMBL12965870 | 0.75 | KDM4E (0.59) | KDM4EHSD17B10LMNACYP1A2MEN1 | |
| SCHEMBL19911168 | 0.74 | HSD17B10 (0.62) | KDM4EHSD17B10LMNACYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586978-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2017-03-07 | — | — | US | disclosed |