Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.44 |
| ▸ | ADH1B | P00325 | 2/20 | 0.42 |
| ▸ | ADH1C | P00326 | 2/20 | 0.42 |
| ▸ | ADH1A | P07327 | 2/20 | 0.42 |
| ▸ | ADH4 | P08319 | 2/20 | 0.42 |
| ▸ | ADH7 | P40394 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775229 | 1.00 | EPHX1 (0.44) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL25588095 | 1.00 | EPHX1 (0.44) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL7770644 | 1.00 | EPHX1 (0.44) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL11150782 | 1.00 | EPHX1 (0.44) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL19006418 | 1.00 | EPHX1 (0.44) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL25100338 | 1.00 | EPHX1 (0.44) | EPHX1ADH1BADH1CADH1AADH4 | |
| Ammonia Solution, Strong SCHEMBL28667087 | 0.98 | EPHX1 (0.42) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL7775122 | 0.98 | TSHR (0.43) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL25492666 | 0.98 | TSHR (0.43) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL24927982 | 0.98 | TSHR (0.43) | EPHX1ADH1BADH1CADH1AADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586978-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2017-03-07 | — | — | US | disclosed |